In most cases, it resolves on its own, but you can experience a relapse. More severe forms can lead to cosmetic deformities, and it occasionally affects the muscle, joints, or bone.
In general, morphea causes discolored, thickened patches of skin that are oval in shape. The outer edge of the lesion may be lilac, and the patch itself is usually reddish in color.
It gradually becomes white or yellow in color toward the center of the oval. This is the most common type. People with plaque-type morphea have three or four oval lesions.
The lesions are painless, but might itch. This involves multiple widespread lesions that are larger. Generalized morphea can affect deeper tissues, which might lead to disfigurement. The lesions can also join together. This is a rapidly progressive type of morphea with many plaques that can cover almost your entire body. It spares hands and feet. This type needs the most aggressive treatment.
Linear morphea features a single band of thickened, discolored skin. Usually, the indented band runs down an arm or leg, but it might also extend down your forehead. Linear morphea is the most common type of morphea found in school-aged children. The lesions may extend to the tissue under their skin, even to their muscles and bones, leading to deformities.
If linear morphea occurs on their face, it might cause issues with their eyes or alignment of their teeth. The registry was established in to learn more about morphea. Little is known about morphea since it is a rare, poorly understood, and understudied condition. This registry will provide a resource for investigators to make discoveries in regard to both the clinical and genetic aspects of the disease.
If you or your child have morphea and are at least 3 years old, you can join the study. If the diagnosis is uncertain, we would still like to see you to perform our own assessment. If you are uncertain about joining or eligibility, feel free to contact us for more information.
Note: children under the age of 18 must be accompanied by a parent or guardian if the child comes to UT Southwestern for enrollment. There are currently more than participants, but we need as many participants as possible to reach our goal. We are currently only able to enroll patients in person. Please contact us by email or phone to set up an appointment. No, but we are conducting a separate double-blinded randomized clinical trial studying the effectiveness of UVA-1 phototherapy for morphea.
Please visit our UVA-1 clinical trial page for more information about the study and eligibility requirements. There is no cost to enroll. Show references AskMayoExpert. Mayo Clinic; Office of Patient Education. Albuquerque JV, et al. Interventions for morphea. Cochrane Database of Systematic Reviews. Jacobe H. Pathogenesis, clinical manifestations, and diagnosis of morphea localized scleroderma in adults. Accessed Aug. Kumar AB, et al. Treatment of morphea with hydroxychloroquine: A retrospective review of 84 patients at Mayo Clinic, There is much to learn about morphea, but its onset could be related to:.
The appearance of morphea usually only affects the skin and its underlying tissue, although it can also affect the bone and muscle. Plaque morphea usually consists of limited oval lesions that appear on the skin.
The lesions are typically painless but may become itchy. Generalized plaque morphea is more widespread than plaque morphea. A person with generalized plaque morphea will have more lesions over a greater area of skin. It can also affect deeper tissues, possibly leading to cosmetic disfigurement and lesions joining together.
This form of morphea is rare and tends to require aggressive treatment. Pansclerotic morphea occurs when the lesions cover almost all of the body. It progresses quickly, and medical intervention is necessary to try to manage it. It usually starts in children. Linear morphea usually occurs on the arms or legs and appears as a single band of thick, discolored skin.
The lesions can cross joints and extend to the tissue under the skin, as well as the muscles and bone. This can lead to deformities. Sometimes, linear morphea appears as a line on the forehead, which can cause problems with eyesight or lead to neurological problems.
This type of morphea is more likely to affect school-aged children.
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